Collect Brain Data
After a patient’s brain has been cryogenically frozen to where all synapse states are preserved, the brain is sliced into thin segments. These slices are scanned and the images from the scans undergo analysis of the structure of the brain tissue. With recognition of structures in the brain, and their relations to the surrounding structures, the functionality of the brain tissue scanned is interpreted and recorded as data.
Extract Neuronal Activities
System identification for each neural circuit depends on a tremendous amount of recorded activity data and, to a lesser extent, on more generic connectome structure data.
Initialize the Model
To begin, we initialize a feasibly-derivable, constrained model with generic knowledge of circuit connectome and suitable kernel functions.