Member Bio: Randal Koene

Randal A. Koene


Randal A. Koene is a Dutch neuroscientist and neuroengineer, and co-founder of, the outreach and roadmapping organization for advancing Substrate-Independent Minds (SIM). Between 2008 and 2010, Koene was Director of the Department of Neuroengineering at the Fatronik-Tecnalia Institute in Spain, the third largest private research organization in Europe. Koene earned his Ph.D. in Computational Neuroscience at the Department of Psychology at McGill University, and his M.Sc. in Electrical Engineering with a specialization in Information Theory at Delft University of Technology. He is a former Professor at the Center for Memory and Brain of Boston University, and is co-founder of the Neural Engineering Corporation of Massachusetts. Koene established the website and first proposed the term and specific approach called whole brain emulation, the purpose of which is the technological accomplishment of mind transfer to a different substrate. His professional research objective is the implementation of whole brain emulation: creating the large-scale high-resolution representations and emulations of activity in neuronal circuitry that are needed in patient-specific neuroprostheses. He is a member of the Oxford working group that convened in 2007 to create the first roadmap toward whole brain emulation.

Koene has professional expertise in computational neuroscience, psychology, information theory, electrical engineering and physics. He organizes neural engineering efforts to obtain and replicate function and structure information that resides in the neural substrate for use in neuroprostheses and neural interfaces. Based on NETMORPH, Koene's computational framework for the simulated morphological development of neuronal circuitry, his lab is creating a Virtual Brain Laboratory to give neuroscientists, neuroengineers and clinicians large-scale high-resolution quantitative tools analogous to the computational tools that have become essential in fields such as genetics, chemistry or the aero-space industry. This effort bridges scales and will help determine how significant functions are encoded robustly in neural ensembles, and how those functions can nevertheless depend in specific ways on the detailed biophysics of particular component physiology. - From

Available Media

As a forerunner in the field of Whole Brain Emulation, Randal has given countless discourses and spoken in various settings/locations. Of his presentations, many are available in video format. (see below)

He is also known to participate in panels and interviews including the Carboncopies Podcast.


The following is a selection of talks given by Randal A. Koene.

TEDx Tallinn

GF2045 2013

An Intro to WBE

Kernel & Neuralink

Brain Preservation

Model Validation

Brain, AI, & Hybrids

Singularity Summit

Extending Life

System Identification



The Binding Problem

GF4025 II

GF2045 III

Advancing SIM

Complex Requirem…

The Time Is Now

Modern Cosmism

AGI & Neurosci…

WIC 2011

25 Watt Bio-Comp…

ASIM 2010

The Big Picture

Unusual Concepts

Future of AGI




The following is a collection of interviews given by Randal.

Future Science Project

Intelligenge Identity Substrates

Philosophical aspects

The Objective Centrist


Colin Hales Conversation

le neuroscientifique

Substrate Independent Minds

Singularity Summit